CAMK2B antibody (C-Term)

Catalog No. ABIN2788742

The Rabbit Polyclonal anti-CAMK2B antibody (ABIN2788742) specifically detects CAMK2B in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio) and Dog samples.

Quick Overview for CAMK2B antibody (C-Term) (ABIN2788742)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reactivity: Human, Rat, Mouse, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CAMK2B Antibody

Binding Specificity: C-Term

Purpose: CAMK2B Antibody - C-terminal region

Sequence: NPHVHVIGED AACIAYIRLT QYIDGQGRPR TSQSEETRVW HRRDGKWQNV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CAMK2B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61268-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CAMK2B

Background:

Targeted Subunit: beta

Background Information: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.

Gene Name: Calcium/calmodulin-dependent protein kinase II beta

Alternative Symbols: CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta

Protein Name: Calcium/calmodulin-dependent protein kinase IIB isoform 2 variant EMBL BAD96423.1

Molecular Weight: 60kDa

Gene ID: 816

NCBI Accession: NP_742075

UniProt: Q53H78

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity