CAMK2B antibody (Middle Region)

Catalog No. ABIN786379

This Rabbit Polyclonal antibody specifically detects CAMK2B in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for CAMK2B antibody (Middle Region) (ABIN786379)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reactivity: Human, Rat, Mouse, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CAMK2B Antibody

Binding Specificity: Middle Region

Sequence: SAKSLLNKKA DGVKPQTNST KNSAAATSPK GTLPPAALEP QTTVIHNPVD

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CAMK2B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 517 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CAMK2B

Background: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.
Alias Symbols: CAM2, CAMK2, CAMKB, MGC29528
Protein Interaction Partner: KRTAP10-11, KRTAP19-7, KRTAP19-5, FAM171A2, MGAT5B, CCM2L, TTC5, AP5B1, MRPL11, SEMA4G, SPRYD7, MED18, POP5, RBFOX2, ACOT7, RBPMS, MORF4L1, MAD2L2, RPL11, RAP2B, PHKB, CAMK2B, MVP, SMYD3, UBC, ATXN1, HSP90AA1, Rad23a, THRB, RXRG, YWHAB, CAMK2N2, CAMK2D, A
Protein Size: 517

Molecular Weight: 57 kDa

Gene ID: 816

NCBI Accession: NM_172080, NP_742077

UniProt: A4D2K5

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity