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MUS81 antibody (C-Term)

MUS81 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2788792
  • Target See all MUS81 Antibodies
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    Binding Specificity
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Pig
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    This MUS81 antibody is un-conjugated
    Application
    • 7
    • 6
    • 4
    • 4
    Western Blotting (WB)
    Sequence
    GETRGGGHRP ELLRELQRLH VTHTVRKLHV GDFVWVAQET NPRDPANPGE
    Predicted Reactivity
    Cow: 79%, Dog: 86%, Human: 100%, Mouse: 79%, Pig: 83%, Rat: 79%
    Characteristics
    This is a rabbit polyclonal antibody against MUS81. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product MUS81 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 551 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    Alternative Name
    MUS81 (MUS81 Products)
    Synonyms
    CG3026 antibody, Dmel\\CG3026 antibody, EG:BACR7A4.16 antibody, MUS81 antibody, GB15332 antibody, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antibody, ATMUS81 antibody, F6I18.220 antibody, F6I18_220 antibody, MMS AND UV SENSITIVE 81 antibody, SLX3 antibody, slx3 antibody, 1200008A18Rik antibody, AI182501 antibody, AW045863 antibody, wu:fc26g01 antibody, zgc:66489 antibody, zgc:91801 antibody, CG3026 gene product from transcript CG3026-RA antibody, MUS81 structure-specific endonuclease subunit antibody, crossover junction endonuclease MUS81 antibody, Restriction endonuclease, type II-like superfamily protein antibody, Mus81p antibody, Holliday junction resolvase subunit Mus81 antibody, MUS81 protein antibody, hypothetical protein antibody, mus81 antibody, MUS81 antibody, LOC725951 antibody, Mus81 antibody, CAALFM_C600540WA antibody
    Background
    MUS81 interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. It may be required in mitosis for the processing of stalled or collapsed replication forks.
    Alias Symbols: FLJ21012, FLJ44872, SLX3
    Protein Interaction Partner: SLX4, vpr, EME1, PLK1, FBXL5, SLX1A, WEE1, EME2, SUMO2, SLX1B, MUS81, CHEK2, TERT, TERF2,
    Protein Size: 551
    Molecular Weight
    61 kDa
    Gene ID
    80198
    NCBI Accession
    NM_025128, NP_079404
    UniProt
    Q96NY9
    Pathways
    DNA Damage Repair
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