Acrosin antibody (C-Term)

Catalog No. ABIN2789340

This Rabbit Polyclonal antibody specifically detects Acrosin in WB. It exhibits reactivity toward Human, Cow, Horse and Sheep.

Quick Overview for Acrosin antibody (C-Term) (ABIN2789340)

Target: Acrosin (ACR)

Reactivity: Human, Cow, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acrosin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Acrosin Antibody

Binding Specificity: C-Term

Purpose: ACR Antibody - C-terminal region

Sequence: GKIDTCQGDS GGPLMCKDSK ESAYVVVGIT SWGVGCARAK RPGIYTATWP

Predicted Reactivity: Cow: 79%, Horse: 79%, Human: 100%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against ACR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63016-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Acrosin

Target: Acrosin (ACR)

Alternative Name: ACR

Background:

Background Information: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

Gene Name: Acrosin

Alternative Symbols: -

Protein Name: Acrosin

Molecular Weight: 46kDa

Gene ID: 49

NCBI Accession: NP_001088

UniProt: P10323

Pathways: cAMP Metabolic Process