NGFR antibody (C-Term)

Catalog No. ABIN2789433

The Rabbit Polyclonal anti-NGFR antibody is suitable to detect NGFR in samples from Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Guinea Pig and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for NGFR antibody (C-Term) (ABIN2789433)

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivity: Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NGFR antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NGFR Antibody

Binding Specificity: C-Term

Purpose: NGFR Antibody - C-terminal region

Sequence: VTRGTTDNLI PVYCSILAAV VVGLVAYIAF KRWNSCKQNK QGANSRPVNQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against NGFR. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63279-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Alternative Name: NGFR

Background:

Background Information: Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.

Gene Name: Nerve growth factor receptor

Alternative Symbols: CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR

Protein Name: Tumor necrosis factor receptor superfamily member 16

Molecular Weight: 47kDa

Gene ID: 4804

NCBI Accession: NP_002498

UniProt: P08138

Pathways: NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding