BAG1 antibody (N-Term)
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- Target See all BAG1 Antibodies
- BAG1 (BCL2-Associated Athanogene (BAG1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BAG1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QGEEMNRSQE VTRDEESTRS EEVTREEMAA AGLTVTVTHS NEKHDLHVTS
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against BAG1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product BAG1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 345 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BAG1 (BCL2-Associated Athanogene (BAG1))
- Alternative Name
- BAG1 (BAG1 Products)
- Synonyms
- BAG-1 antibody, HAP antibody, RAP46 antibody, Rap46 antibody, Bag-1 antibody, ATBAG1 antibody, BCL-2-associated athanogene 1 antibody, MSG15.15 antibody, MSG15_15 antibody, im:7148830 antibody, si:dkey-216e9.4 antibody, BCL2 associated athanogene 1 antibody, putative bcl2-associated athanogene antibody, BCL2-associated athanogene 1 antibody, Bcl2 associated athanogene 1 antibody, BAG family molecular chaperone regulator 1 antibody, BCL-2-associated athanogene 1 antibody, BAG1 antibody, Smp_005900 antibody, Bag1 antibody, bag-1 antibody, LOC781741 antibody, bag1 antibody
- Background
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The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: TRIM27, PSMD2, HSPA8, TRIM23, LTN1, DNAJB4, STUB1, DNAJB6, MLF2, DNAJB1, SHFM1, CD44, NIF3L1, RPRD1B, XPO5, OSGEP, PANK4, PEG10, ANP32B, ACTR2, ARPC4, TOM1L1, ZPR1, FUBP1, ANP32A, SH3GL1, GRPEL1, EFTUD1, RPA3, RANGAP1, NR3C1, RAF1, HSPA4, PYGL, ARRB1, UBC
Protein Size: 345 - Molecular Weight
- 38 kDa
- Gene ID
- 573
- NCBI Accession
- NM_004323, NP_004314
- UniProt
- Q99933
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