CNR2 antibody (C-Term)

Catalog No. ABIN970425

Product Details anti-CNR2 Antibody

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MVNPVIYALR SGEIRSSAHH CLAHWKKCVR GLGSEAKEEA PRSSVTETEA

Predicted Reactivity: Horse: 83%, Human: 100%, Mouse: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CNR2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 360 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CNR2 antibody (ABIN970425)

Wilhelmsen, Khakpour, Tran, Sheehan, Schumacher, Xu, Hellman: "The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13079-100, (2014) (PubMed).

Target Details for CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Alternative Name: CNR2 (CNR2 Products)

Synonyms: CNR2 antibody, CB2 antibody, cb2a antibody, cb2b antibody, CB-2 antibody, CX5 antibody, CB2C antibody, CNR2C antibody, CB2-R antibody, cannabinoid receptor 2 antibody, cannabinoid receptor 2 (macrophage) antibody, CNR2 antibody, cnr2 antibody, Cnr2 antibody

Background: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Alias Symbols: CB2, CX5
Protein Interaction Partner: GNA15,
Protein Size: 360

Molecular Weight: 40 kDa

Gene ID: 1269

NCBI Accession: NM_001841, NP_001832

UniProt: P34972