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CRHR1 antibody (C-Term)

CRHR1 Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Sheep, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789561
  • Target See all CRHR1 Antibodies
    CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
    Binding Specificity
    • 15
    • 15
    • 9
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 63
    • 63
    • 61
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Horse, Cow, Sheep, Rabbit, Guinea Pig, Zebrafish (Danio rerio)
    Host
    • 86
    • 5
    • 2
    Rabbit
    Clonality
    • 88
    • 5
    Polyclonal
    Conjugate
    • 36
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This CRHR1 antibody is un-conjugated
    Application
    • 75
    • 37
    • 30
    • 26
    • 20
    • 16
    • 11
    • 8
    • 6
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    RPGVYTDYIY QGPMILVLLI NFIFLFNIVR ILMTKLRAST TSETIQYRKA
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CRHR1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product CRHR1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 401 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CRHR1 (Corticotropin Releasing Hormone Receptor 1 (CRHR1))
    Alternative Name
    CRHR1 (CRHR1 Products)
    Synonyms
    CRF-R antibody, CRF-R-1 antibody, CRF-R1 antibody, CRF1 antibody, CRFR-1 antibody, CRFR1 antibody, CRH-R-1 antibody, CRH-R1 antibody, CRH-R1h antibody, CRHR antibody, CRHR1L antibody, CRHR1f antibody, Crhr antibody, crhr1 antibody, crhr1-A antibody, CRHR1 antibody, CRHR1-IT1-CRHR1 antibody, MGC57346-CRHR1 antibody, corticotropin releasing hormone receptor 1 antibody, corticotropin releasing hormone receptor 1, gene 2 S homeolog antibody, corticotropin-releasing factor receptor 1 antibody, LINC02210-CRHR1 readthrough antibody, CRHR1 antibody, Crhr1 antibody, crhr1.2.S antibody, LOC610380 antibody, LOC100065598 antibody, LINC02210-CRHR1 antibody, crhr1 antibody
    Background
    This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.
    Alias Symbols: CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1L, CRHR1f, CRF-R1, CRFR-1, CRH-R1, CRF-R-1, CRH-R-1
    Protein Interaction Partner: SRPK1, GNAI1, CALM1, UCN3, CRH, GNAQ, UCN, GNAS, GNAO1,
    Protein Size: 401
    Molecular Weight
    44 kDa
    Gene ID
    1394
    NCBI Accession
    NM_001145148, NP_001138620
    Pathways
    Hormone Transport, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Feeding Behaviour, Negative Regulation of Transporter Activity
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