IFNGR1 antibody (C-Term)

Catalog No. ABIN2789606

Product Details anti-IFNGR1 Antibody

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNGR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EVDYDPETTC YIRVYNVYVR MNGSEIQYKI LTQKEDDCDE IQCQLAIPVS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IFNGR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human IFNGR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Alternative Name: IFNGR1 (IFNGR1 Products)

Synonyms: CD119 antibody, IFNGR antibody, IFN-gammaR antibody, Ifgr antibody, Ifngr antibody, Nktar antibody, IFNGR1 antibody, MGC129098 antibody, ifngr1 antibody, MGC194858 antibody, MGC194873 antibody, zgc:194858 antibody, cd119 antibody, ifngr antibody, DKFZp469K1232 antibody, interferon gamma receptor 1 antibody, cytokine receptor family member B17 antibody, IFNGR1 antibody, Ifngr1 antibody, crfb17 antibody, ifngr1 antibody

Background: This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Alias Symbols: CD119, IFNGR, IMD27A, IMD27B
Protein Size: 274

Molecular Weight: 30 kDa

Gene ID: 3459

NCBI Accession: NM_000416, NP_000407

UniProt: P15260

Pathways: Interferon-gamma Pathway