PAG1 antibody (C-Term)
Quick Overview for PAG1 antibody (C-Term) (ABIN2789626)
Target
See all PAG1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- PNSTLPPAGR PSEEPEPDYE AIQTLNREEE KATLGTNGHH GLVPKENDYE
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Predicted Reactivity
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against PAG1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 432 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
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Alternative Name
- PAG1
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Background
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The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation.
Alias Symbols: CBP, FLJ37858, MGC138364, PAG
Protein Interaction Partner: PAG1, CSK, HTRA2, GLS2, SLC9A3R1, LCP2, SHC1, SYK, ABL1, ZAP70, PTPN6, PTPN11, LYN, VAV1, LCK, RASA1, FYN, GRB2,
Protein Size: 432 -
Molecular Weight
- 47 kDa
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Gene ID
- 55824
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NCBI Accession
- NM_018440, NP_060910
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UniProt
- Q9NWQ8
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Pathways
- p53 Signaling, TCR Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
Target
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