TP53I3 antibody (C-Term)

Catalog No. ABIN2789865

The Rabbit Polyclonal anti-TP53I3 antibody (ABIN2789865) specifically detects TP53I3 in WB. The antibody is reactive with Human, Rat, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for TP53I3 antibody (C-Term) (ABIN2789865)

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reactivity: Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53I3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TP53I3 Antibody

Binding Specificity: C-Term

Purpose: TP53I3 Antibody - C-terminal region

Sequence: SKLLFKRGSL ITSLLRSRDN KYKQMLVNAF TEQILPHFST EGPQRLLPVL

Predicted Reactivity: Cow: 86%, Dog: 85%, Horse: 83%, Human: 100%, Pig: 93%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TP53I3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TP53I3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64531-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TP53I3

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Alternative Name: TP53I3

Background:

Background Information: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.

Gene Name: Tumor protein p53 inducible protein 3

Alternative Symbols: PIG3

Protein Name: Tumor protein p53 inducible protein 3, isoform CRA_c EMBL EAX00765.1

Molecular Weight: 26kDa

Gene ID: 9540

UniProt: B4DMQ7

Pathways: p53 Signaling