ITGA5 antibody (C-Term)

Catalog No. ABIN2789900

Product Details anti-ITGA5 Antibody

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RVTGLNCTTN HPINPKGLEL DPEGSLHHQQ KREAPSRSSA SSGPQILKCP

Predicted Reactivity: Human: 100%, Mouse: 77%

Characteristics: This is a rabbit polyclonal antibody against ITGA5. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1049 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: ITGA5 (ITGA5 Products)

Synonyms: ITGA5 antibody, Cd49e antibody, Fnra antibody, VLA5 antibody, CD49e antibody, FNRA antibody, VLA5A antibody, Itga5_retired antibody, integrin subunit alpha 5 antibody, integrin alpha 5 (fibronectin receptor alpha) antibody, ITGA5 antibody, Itga5 antibody

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Alias Symbols: CD49e, FNRA, VLA5A
Protein Interaction Partner: FBXO6, STAMBP, UBC, GRK6, FN1, EWSR1, FUBP1, ITGB1, HNRNPU, SHARPIN, PLP1, CALR, FGFR2, CBL, NISCH, ANGPTL3, GIPC1, ARHGAP5, AUP1, ANGPT1, L1CAM, TNC, ITGB3, PECAM1, SPP1, ERBB2, ITGB5, CD9, FLT4, EGFR, COL18A1, COL1A1, RABIF, ILK,
Protein Size: 1049

Molecular Weight: 110 kDa

Gene ID: 3678

NCBI Accession: NM_002205, NP_002196

UniProt: P08648

Pathways: Integrin Complex