PPP3CC antibody (C-Term)

Catalog No. ABIN2789946

The Rabbit Polyclonal anti-PPP3CC antibody (ABIN2789946) specifically detects PPP3CC in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for PPP3CC antibody (C-Term) (ABIN2789946)

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP3CC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP3CC Antibody

Binding Specificity: C-Term

Purpose: PPP3CC Antibody - C-terminal region

Sequence: FTEPPAFGPV CDLLWSDPSE DYGNEKTLEH YTHNTVRGCS YFYSYPAVCE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PPP3CC. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64741-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP3CC

Target: PPP3CC (Protein Phosphatase 3, Catalytic Subunit, gamma Isozyme (PPP3CC))

Alternative Name: PPP3CC

Background:

Targeted Subunit: gamma isoform

Background Information: Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.

Gene Name: Protein phosphatase 3, catalytic subunit, gamma isozyme

Alternative Symbols: CNA3, CALNA3, PP2Bgamma

Protein Name: Serine/threonine-protein phosphatase RuleBase RU004273

Molecular Weight: 35kDa

Gene ID: 5533

UniProt: G3V111

Pathways: RTK Signaling, WNT Signaling, VEGF Signaling, BCR Signaling