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DCLK1 antibody (C-Term)

DCLK1 Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2789984
  • Target See all DCLK1 Antibodies
    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
    Binding Specificity
    • 16
    • 15
    • 9
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 85
    • 45
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog
    Host
    • 84
    • 6
    • 1
    Rabbit
    Clonality
    • 76
    • 15
    Polyclonal
    Conjugate
    • 34
    • 9
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCLK1 antibody is un-conjugated
    Application
    • 72
    • 43
    • 20
    • 17
    • 13
    • 13
    • 9
    • 9
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    IFIACGPEKF RYQDDFLLDE SECRVVKSTS YTKIASSSRR STTKSPGPSR
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against DCLK1. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of human DCLK1
    Top Product
    Discover our top product DCLK1 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
    Alternative Name
    DCLK1 (DCLK1 Products)
    Synonyms
    DCLK1 antibody, DCAMKL1 antibody, dcamkl1 antibody, dclk1 antibody, wu:fc51f11 antibody, zgc:153709 antibody, MGC145348 antibody, CL1 antibody, CLICK1 antibody, DCDC3A antibody, DCLK antibody, 1700113D08Rik antibody, 2810480F11Rik antibody, AI836758 antibody, Click-I antibody, Cpg16 antibody, Dcamkl1 antibody, Dcl antibody, Dclk antibody, mKIAA0369 antibody, Ania4 antibody, doublecortin like kinase 1 antibody, doublecortin-like kinase 1a antibody, serine/threonine-protein kinase DCLK1 antibody, doublecortin-like kinase 2 antibody, doublecortin-like kinase 1 antibody, DCLK1 antibody, dclk1a antibody, LOC587664 antibody, dclk2 antibody, LOC100539645 antibody, Dclk1 antibody
    Background
    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.
    Alias Symbols: CL1, DCLK, CLICK1, DCDC3A, DCAMKL1
    Protein Size: 363
    Molecular Weight
    39 kDa
    Gene ID
    9201
    NCBI Accession
    NM_001195415, NP_001182344
    UniProt
    O15075
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