PSMB11 antibody (C-Term)

Catalog No. ABIN2790679

Product Details anti-PSMB11 Antibody

Target: PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

Binding Specificity: C-Term

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: HVRESGWEHV SRSDACVLYV ELQKLLEPEP EEDASHAHPE PATAHRAAED

Predicted Reactivity: Human: 100%, Rat: 83%

Characteristics: This is a rabbit polyclonal antibody against PSMB11. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PSMB11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 300 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSMB11

Target: PSMB11 (Proteasome (Prosome, Macropain) Subunit, beta Type, 11 (PSMB11))

Alternative Name: PSMB11 (PSMB11 Products)

Synonyms: BETA5T antibody, 5830406J20Rik antibody, beta5t antibody, proteasome subunit beta 11 antibody, proteasome (prosome, macropain) subunit, beta type, 11 antibody, PSMB11 antibody, Psmb11 antibody

Background: Proteasomes generate peptides that are presented by major histocompatibility complex (MHC) I molecules to other cells of the immune system. Proteolysis is conducted by 20S proteasomes, complexes of 28 subunits arranged as a cylinder in 4 heteroheptameric rings: alpha-1 to -7, beta-1 to -7, beta-1 to -7, and alpha-1 to -7. The catalytic subunits are beta-1, beta-2), and beta-5 (PSMB5, MIM 600306). Three additional subunits, beta-1i, beta-2i, and beta-5i, are induced by gamma-interferon and are preferentially incorporated into proteasomes to make immunoproteasomes. PSMB11, or beta-5t, is a catalytic subunit expressed exclusively in cortical thymic epithelial cells .
Alias Symbols: BETA5T
Protein Size: 300

Molecular Weight: 33 kDa

Gene ID: 122706

NCBI Accession: NM_001099780, NP_001093250

UniProt: A5LHX3