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FAK antibody (Middle Region)
PTK2
Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Rabbit, Horse, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FAK Antibody
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Target
See all FAK (PTK2) Antibodies
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Binding Specificity
All epitopes for FAK antibodies
Middle Region
Reactivity
All reactivities for FAK antibodies
Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Rabbit, Horse, Guinea Pig
Host
All hosts for FAK antibodies
Rabbit
Clonality
All clonalities for FAK antibodies
Polyclonal
Conjugate
All conjugates for FAK antibodies
This FAK antibody is un-conjugated
Application
All applications for FAK antibodies
Western Blotting (WB)
Sequence
SEKQGMRTHA VSVSETDDYA EIIDEEDTYT MPSTRDYEIQ RER IELGRC
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
Characteristics
This is a rabbit polyclonal antibody against PTK2. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human PTK2
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for FAK
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Target
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Alternative Name
PTK2 (PTK2 Products )
Synonyms
FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody
Background
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. Protein Interaction Partner: DEF6, SOCS3, YES1, IQGAP1, UBE2H, UBC, TRIM72, SRPK1, PXN, PTRH2, SAE1, HSP90AA1, APP, RBSN, BCAR1, KCNJ3, PTAFR, STAT1, CBL, STAP2, STUB1, PTPN11, PPP1CB, PPP1CA, SRC, CTTN, ASAP1, SH3KBP1, PDCD6IP, ITGB5, ELAVL1, DAG1, GRB2, FBP1, F13A1, EEF1G, LPXN, TG Protein Size: 431
Molecular Weight
47 kDa
Gene ID
5747
Pathways
Response to Growth Hormone Stimulus , CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling
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