GSK3 alpha antibody (N-Term)

Catalog No. ABIN2792115

This Rabbit Polyclonal antibody specifically detects GSK3 alpha in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog and Pig.

Quick Overview for GSK3 alpha antibody (N-Term) (ABIN2792115)

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSK3 alpha Antibody

Binding Specificity: N-Term

Sequence: MSGGGPSGGG PGGSGRARTS SFAEPGGGGG GGGGGPGGSA SGPGGTGGGK

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GSK3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSK3A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 483 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GSK3 alpha

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Alternative Name: GSK3A

Background: GSK3alpha is a potential regulator of platelet function and improves insulin action and glucose metabolism in skeletal muscle.
Protein Interaction Partner: NBR1, UBC, GSKIP, AKAP9, FRAT1, AXIN2, AXIN1, PSMD1, PPP1R2, GSK3A, DEAF1, ARHGEF11, PRKDC, PRKCH, PRKCG, PRKCD, PRKCB, PRKCA, MAP3K11, HSP90AA1, AKT1, Prune, Lzts2, Gm4779, Spice1, Krba1, Prox2, Zbed3, Vta1, Nono, FAM193B, SPG21, PRKACA, MAPT, GLI3, CREB
Protein Size: 483

Molecular Weight: 51 kDa

Gene ID: 2931

NCBI Accession: NM_019884, NP_063937

UniProt: P49840

Pathways: PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect