RAD9A antibody (C-Term)
-
- Target See all RAD9A Antibodies
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
-
Binding Specificity
- C-Term
-
Reactivity
- Human, Horse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This RAD9A antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Sequence
- SLSPGPQPPK SPGPHSEEED EAEPSTVPGT PPPKKFRSLF FGSILAPVRS
- Predicted Reactivity
- Horse: 84%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against RAD9A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RAD9A
- Top Product
- Discover our top product RAD9A Primary Antibody
-
-
- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
-
Antigen size: 391 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
- Alternative Name
- RAD9A (RAD9A Products)
- Synonyms
- RAD9 antibody, Rad9 antibody, rad9a antibody, MGC89062 antibody, XRad9 antibody, rad9 antibody, RAD9 checkpoint clamp component A antibody, RAD9 checkpoint clamp component B antibody, RAD9 checkpoint clamp component A L homeolog antibody, RAD9A antibody, Rad9a antibody, rad9a antibody, rad9b antibody, rad9a.L antibody
- Background
-
RAD9A is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. ADPGK (EC 2.7.1.147) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM].
Alias Symbols: RAD9
Protein Interaction Partner: ATRX, BCL2L1, CLSPN, RAD17, MSH3, MSH2, MSH6, FEM1B, COPS5, UBC, PCNA, SF3B3, DNMT1, SETMAR, ATR, TOPBP1, HUS1B, RAD9B, ITSN2, ATAD5, DNAJC7, ATM, CHEK2, HUS1, HDAC1, AR, ABL1, BCL2, MLH1, FEN1, RPA2, RPA1, RAD1, NR3C1,
Protein Size: 391 - Molecular Weight
- 42 kDa
- Gene ID
- 5883
- NCBI Accession
- NM_004584, NP_004575
- UniProt
- Q99638
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
-