PRPF4B antibody (C-Term)

Catalog No. ABIN2793061

Product Details anti-PRPF4B Antibody

Target: PRPF4B (Serine/threonine-Protein Kinase PRP4 Homolog (PRPF4B))

Binding Specificity: AA 948-978, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF4B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human PRP4 (C-term) Antibody

Immunogen: This PRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 948-978 amino acids from the C-terminal region of human PRP4.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100Western blot analysis of anti-PRP4 Pab was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. BC = breast carcinoma, HC = hepatocarcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PRPF4B

Target: PRPF4B (Serine/threonine-Protein Kinase PRP4 Homolog (PRPF4B))

Alternative Name: PRP4 (PRPF4B Products)

Synonyms: PR4H antibody, PRP4 antibody, PRP4H antibody, PRP4K antibody, dJ1013A10.1 antibody, 2610037H07 antibody, Prp4 antibody, Prp4k antibody, Prpk antibody, cbp143 antibody, prpf4b antibody, wu:fc18e10 antibody, wu:fe47g02 antibody, zgc:55623 antibody, DKFZp469K1914 antibody, pre-mRNA processing factor 4B antibody, pre-mRNA processing factor 4Bb antibody, serine/threonine-protein kinase PRP4 homolog antibody, PRPF4B antibody, Prpf4b antibody, prpf4bb antibody, prpf4b antibody, LOC100169542 antibody, LOC100634371 antibody, LOC100639201 antibody

Background:

Target Description: Pre-mRNA splicing occurs in two sequential transesterification steps, and PRP4 is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases (CDKs). This protein is regarded as a CDK-like kinase (Clk) with homology to mitogen-activated protein kinases (MAPKs).

Gene Symbol: PRPF4B

Molecular Weight: 116987 Da

Gene ID: 8899

UniProt: Q13523