MAP3K1 antibody (pThr1383)

Catalog No. ABIN2794172

The Rabbit Polyclonal anti-MAP3K1 antibody has been validated for DB. It is suitable to detect MAP3K1 in samples from Human.

Quick Overview for MAP3K1 antibody (pThr1383) (ABIN2794172)

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K1 antibody is un-conjugated

Application: Dot Blot (DB)

Product Details anti-MAP3K1 Antibody

Binding Specificity: pThr1383

Purpose: Rabbit Anti-Human Phospho-MAP3K1(T1383) Antibody

Immunogen: This MAP3K1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1383 of human MAP3K1.

Isotype: Ig Fraction

Application Details

Application Notes: Dot Blot
Recommended Dilutions
DB: 1:500
Dot blot analysis of Phospho-MAP3K1-T1383 Pab on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration were 0.5 μg per ml.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for MAP3K1

Target: MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1 (MAP3K1))

Alternative Name: MAP3K1

Background:

Target Description: Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.

Gene Symbol: MAP3K1

Molecular Weight: 164470 Da

Gene ID: 4214

UniProt: Q13233

Pathways: MAPK Signaling, Interferon-gamma Pathway, Caspase Cascade in Apoptosis, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Actin Filament Polymerization, Toll-Like Receptors Cascades