CRYGD antibody (Center)

Catalog No. ABIN2795497

Product Details anti-CRYGD Antibody

Target: CRYGD (Crystallin, gamma D (CRYGD))

Binding Specificity: AA 73-101, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRYGD antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human CRYGD (Center) Antibody

Immunogen: This CRYGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-101 amino acids from the Central region of human CRYGD.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000CRYGD Antibody (Center).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CRYGD

Target: CRYGD (Crystallin, gamma D (CRYGD))

Alternative Name: CRYGD (CRYGD Products)

Synonyms: ccp antibody, caca antibody, cca3 antibody, cryg4 antibody, cry-g-d antibody, MGC85594 antibody, CRYGD antibody, CACA antibody, CCA3 antibody, CCP antibody, CRYG4 antibody, CTRCT4 antibody, PCC antibody, cry-g-D antibody, Aey4 antibody, Cryg-1 antibody, DGcry-1 antibody, Lop12 antibody, Cryg4 antibody, Len antibody, crystallin gamma D L homeolog antibody, crystallin gamma D antibody, crystallin, gamma D antibody, crygd.L antibody, CRYGD antibody, Crygd antibody

Background:

Target Description: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Gene Symbol: CRYGD

Molecular Weight: 20738 Da

Gene ID: 1421

UniProt: P07320