PCDHGA8 antibody (C-Term)
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- Target See all PCDHGA8 Antibodies
- PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))
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Binding Specificity
- AA 781-808, C-Term
- Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PCDHGA8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Purpose
- Rabbit Anti-Human PCDHGA8 (C-term) Antibody
- Immunogen
- This PCDHGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human PCDHGA8.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PCDHGA8 Primary Antibody
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- Application Notes
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Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50PCDHGA8 Antibody (C-term) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.320 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))
- Alternative Name
- PCDHGA8 (PCDHGA8 Products)
- Synonyms
- PCDH-GAMMA-A8 antibody, PCDHGB5 antibody, mKIAA4054 antibody, protocadherin gamma subfamily A, 8 antibody, PCDHGA8 antibody, Pcdhga8 antibody
- Background
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Target Description: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Gene Symbol: PCDHGA8
- Molecular Weight
- 101480 Da
- Gene ID
- 9708
- UniProt
- Q9Y5G5
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