SIM1 antibody (N-Term)

Catalog No. ABIN2797974

Product Details anti-SIM1 Antibody

Target: SIM1 (Single-Minded Homolog 1 (SIM1))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: Rabbit Anti-Human SIM1 (N-term) Antibody

Immunogen: This SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SIM1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from 293T cell line, using SIM1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.500 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for SIM1

Target: SIM1 (Single-Minded Homolog 1 (SIM1))

Alternative Name: SIM1 (SIM1 Products)

Synonyms: bHLHe14 antibody, mSIM1 antibody, single-minded family bHLH transcription factor 1 antibody, single-minded homolog 1 (Drosophila) antibody, single-minded family bHLH transcription factor 1a antibody, SIM1 antibody, Sim1 antibody, sim1a antibody

Background:

Target Description: SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.

Gene Symbol: SIM1

Molecular Weight: 85515 Da

Gene ID: 6492

UniProt: P81133