HBG1 antibody (Center)

Catalog No. ABIN2798240

Product Details anti-HBG1 Antibody

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Binding Specificity: AA 56-85, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBG1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human HBG1 (Center) Antibody

Immunogen: This HBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the Central region of human HBG1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of HBG1 (arrow) using rabbit polyclonal HBG1 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for HBG1

Target: HBG1 (Hemoglobin, gamma A (HBG1))

Alternative Name: HBG1 (HBG1 Products)

Synonyms: Hbe1 antibody, Hbb-y antibody, HBGA antibody, HBGR antibody, HSGGL1 antibody, beta-globin antibody, hbb1 antibody, hbga antibody, hbgr antibody, hsggl1 antibody, HBG2 antibody, HBG1 antibody, hemoglobin subunit gamma 1 antibody, hemoglobin subunit gamma 1 L homeolog antibody, hemoglobin, gamma G antibody, hemoglobin subunit gamma-1 antibody, Hbg1 antibody, HBG1 antibody, hbg1.L antibody, LOC100982657 antibody

Background:

Target Description: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Gene Symbol: HBG1

Molecular Weight: 16140 Da

Gene ID: 3047

UniProt: P69891