ARHGEF6 antibody (C-Term)

Catalog No. ABIN2799172

Product Details anti-ARHGEF6 Antibody

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Binding Specificity: AA 614-641, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF6 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human ARHGEF6 (C-term) Antibody

Immunogen: This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000ARHGEF6 Antibody (C-term) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for ARHGEF6

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Alternative Name: ARHGEF6 (ARHGEF6 Products)

Synonyms: COOL2 antibody, Cool-2 antibody, MRX46 antibody, PIXA antibody, alpha-PIX antibody, alphaPIX antibody, 1600028C08Rik antibody, 1700038J06Rik antibody, 4930592P22Rik antibody, Rac/Cdc42 guanine nucleotide exchange factor 6 antibody, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody, ARHGEF6 antibody, Arhgef6 antibody

Background:

Target Description: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq].

Gene Symbol: ARHGEF6

Molecular Weight: 87499 Da

Gene ID: 9459

UniProt: Q15052

Pathways: Neurotrophin Signaling Pathway