Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1) (AA 34-111) antibody (Alexa Fluor 594)

Catalog No. ABIN2804640

Product Details

Target: Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)

Binding Specificity: AA 34-111

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Alexa Fluor 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NADE/NGFRAP1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Nerve Growth Factor Receptor (TNFRSF16) Associated Protein 1 (NGFRAP1)

Alternative Name: NGFRAP1 (NGFRAP1 Products)

Synonyms: BEX3 antibody, Bex antibody, DXS6984E antibody, HGR74 antibody, NADE antibody, NGFRAP1 antibody, LNGFR antibody, Tnfrsf16 antibody, p75 antibody, p75NGFR antibody, p75NTR antibody, AL033356 antibody, Bex3 antibody, DXWsu67e antibody, Gcap27 antibody, Nade antibody, WBP5 antibody, brain expressed X-linked 3 antibody, nerve growth factor receptor (TNFR superfamily, member 16) antibody, BEX3 antibody, Ngfr antibody, Bex3 antibody

Background:

Synonyms: BEX3, BEX3_HUMAN, Brain expressed X linked 3 mouse homolog, Brain-expressed X-linked protein 3, Nerve growth factor receptor TNFRSF16 associated protein 1, Nerve growth factor receptor associated protein 1, Nerve growth factor receptor-associated protein 1, NGFRAP1, Ovarian granulosa cell 13.0 kDa protein HGR74, Ovarian granulosa cell protein, p75NTR associated cell death executor, p75NTR-associated cell death executor, Protein BEX3.

Background: May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.Tissue specificity: Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.

Gene ID: 27018

Pathways: Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity