Mu Opioid Receptor 1 antibody (Opioid Receptor, mu 1) (AA 161-187)

Details for Product anti-OPRM1 Antibody No. ABIN2842674, Supplier: Log in to see
Antigen
  • LMOR
  • M-OR-1
  • MOP
  • MOR
  • MOR1
  • OPRM
  • MOP-R
  • MOR-1
  • MOR-1O
  • Oprm
  • mor
  • muOR
  • MORA
  • Oprrm1
  • or2
  • ZFOR2
  • OPRM1
  • opioid receptor mu 1
  • opioid receptor, mu 1
  • outer membrane protein OprM
  • OPRM1
  • Oprm1
  • oprm1
  • oprM1
Alternatives
anti-Rat (Rattus) Mu Opioid Receptor 1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 161-187, Center
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Reactivity
Human, Mouse (Murine)
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Host
Rabbit
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Clonality (Clone)
Polyclonal ()
Conjugate
This Mu Opioid Receptor 1 antibody is un-conjugated
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Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Options
Supplier
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Immunogen This OPRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 AA from the Central region of human OPRM1.
Clone RB22405
Isotype Ig Fraction
Specificity This OPRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167~196 amino acids from the Center region of human OPRM1.
Predicted Reactivity Pig (Porcine),Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Plasmids, Primers & others Plasmids, Primers & others Mu Opioid Receptor 1 products on genomics-online (e.g. as negative or positive controls)
Antigen Opioid Receptor, mu 1 (OPRM1)
Alternative Name OPRM1 (OPRM1 Antibody Abstract)
Background OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin (see POMC, MIM 176830) and the enkephalins (see PENK, MIM 131330). The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998 [PubMed 9689128]). There are at least 3 types of opioid receptors, mu, kappa (OPRK1, MIM 165196), and delta, each with a distinct pharmacologic profile.
Synonyms: Mu opiate receptor, Mu opioid receptor, MOP, hMOP, Mu-type opioid receptor, M-OR-1, MOR-1, MOR1, OPRM1
Molecular Weight 44779 DA
Gene ID 4988
UniProt P35372
Pathways cAMP Metabolic Process, Synaptic Membrane
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Opioid Receptor, mu 1 (OPRM1) (AA 161-187), (Center) antibody (ABIN2842674) Western blot analysis of OPRM1 Antibody (Center) (ABIN653074) in mouse heart tissue l...
Flow Cytometry (FACS) image for anti-Opioid Receptor, mu 1 (OPRM1) (AA 161-187), (Center) antibody (ABIN2842674) OPRM1 Antibody (Center) (ABIN653074) flow cytometry analysis of K562 cells (bottom hi...
Background publications Wang, Johnson, Persico, Hawkins, Griffin, Uhl: "Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment." in: FEBS letters, Vol. 338, Issue 2, pp. 217-22, 1994 (PubMed).

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