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Poliovirus Receptor antibody (FITC)
PVR
Reactivity: Human
FACS
Host: Rat
Monoclonal
TX21
FITC
Product Details anti-Poliovirus Receptor Antibody (FITC)
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Target
See all Poliovirus Receptor (PVR) Antibodies
Poliovirus Receptor (PVR)
Reactivity
All reactivities for Poliovirus Receptor antibodies
Human
Host
All hosts for Poliovirus Receptor antibodies
Rat
Clonality
All clonalities for Poliovirus Receptor antibodies
Monoclonal
Conjugate
All conjugates for Poliovirus Receptor antibodies
This Poliovirus Receptor antibody is conjugated to FITC
Application
All applications for Poliovirus Receptor antibodies
Flow Cytometry (FACS)
Specificity
This antibody reacts with human CD155.
Purification
Protein G agarose
Immunogen
Recombinant human CD155
Clone
TX21
Isotype
IgG2a
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS, 0.09 % NaN3, 1 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2-8 °C.
Target Details for Poliovirus Receptor
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Target
Poliovirus Receptor (PVR)
Alternative Name
CD155 / PVR (PVR Products )
Synonyms
PVR antibody, CD155 antibody, HVED antibody, NECL5 antibody, Necl-5 antibody, PVS antibody, TAGE4 antibody, 3830421F03Rik antibody, D7Ertd458e antibody, Taa1 antibody, Tage4 antibody, mE4 antibody, necl-5 antibody, poliovirus receptor antibody, PVR antibody, Pvr antibody
Background
CD155, transmembrane glycoprotein, is a member of the immunoglobulin superfamily also known as the human receptor for poliovirus (PVR). CD155 localizes in cell-matrix adhesions and cell-cell junctions. PV receptor CD155 forms a complex with PV (PV1, PV2, and PV3). Both glycosylated and fully deglycosylated CD155 exhibited similar binding sites and orientations in the viral canyon for all three PV serotypes, showing that all three serotypes use a common mechanism for cell entry. It is reported that CD155 and CD112/nectin-2/PRR-2 are ligands of CD226/DNAM-1.Synonyms: Necl-5, Necl5, Nectin-like protein 5, PVS, Poliovirus receptor
Gene ID
5817
NCBI Accession
NP_001129240
UniProt
P15151
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cell-Cell Junction Organization , Cancer Immune Checkpoints , SARS-CoV-2 Protein Interactome
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