TTR antibody
-
- Target See all TTR Antibodies
- TTR (Transthyretin (TTR))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TTR antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
-
Rabbit Polyclonal antibody to Transthyretin (transthyretin)
Transthyretin antibody [N1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Full length human Prealbumin Recombinant protein.
- Isotype
- IgG
- Top Product
- Discover our top product TTR Primary Antibody
-
-
- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
-
Positive Control: rat plasma
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.58 mg/mL
- Buffer
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- Target
- TTR (Transthyretin (TTR))
- Alternative Name
- transthyretin (TTR Products)
- Synonyms
- zgc:103583 antibody, TTR antibody, LOC100226992 antibody, CTS antibody, CTS1 antibody, HsT2651 antibody, PALB antibody, TBPA antibody, AA408768 antibody, AI787086 antibody, D17860 antibody, prealbumin antibody, Lr1 antibody, Tbpa antibody, Prealbumin antibody, xTTR antibody, transthyretin (prealbumin, amyloidosis type I) antibody, transthyretin antibody, Transthyretin antibody, transthyretin (prealbumin, amyloidosis type 1) antibody, transthyretin-like antibody, transthyretin L homeolog antibody, ttr antibody, TTR antibody, vpb38 antibody, MRAD2831_RS38185 antibody, Caci_4246 antibody, LOC100226992 antibody, Ttr antibody, ttr.L antibody
- Background
-
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
Cellular Localization: Secreted , Cytoplasm - Molecular Weight
- 16 kDa
- Gene ID
- 7276
- UniProt
- P02766
- Pathways
- Hormone Transport
-