PSMB4 antibody

Catalog No. ABIN2854353

Product Details anti-PSMB4 Antibody

Target: PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB4 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Characteristics: Rabbit polyclonal antibody to Proteasome beta 4 (proteasome (prosome, macropain) subunit, beta type, 4)
Proteasome beta 4 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Proteasome beta 4. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.73 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PSMB4

Target: PSMB4 (Proteasome (Prosome, Macropain) Subunit, beta Type, 4 (PSMB4))

Alternative Name: proteasome subunit beta 4 (PSMB4 Products)

Synonyms: An18g06680 antibody, PSMB4 antibody, Pros-27 antibody, HN3 antibody, HsN3 antibody, PROS-26 antibody, PROS26 antibody, im:6909492 antibody, zgc:110330 antibody, proteasome subunit beta type-4 antibody, proteasome subunit beta 4 antibody, proteasome (prosome, macropain) subunit, beta type 4 antibody, proteasome subunit beta 4 L homeolog antibody, ANI_1_890164 antibody, PSMB4 antibody, psmb4 antibody, Psmb4 antibody, psmb4.L antibody

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.

Cellular Localization: Cytoplasm (By similarity) , Nucleus

Molecular Weight: 29 kDa

Gene ID: 5692

UniProt: P28070

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA