GNB2L1 antibody (Center)

Catalog No. ABIN2855304

Product Details anti-GNB2L1 Antibody

Target: GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB2L1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Pig (Porcine), Chicken, Cow (Bovine)

Cross-Reactivity (Details): Human (100 %), Mouse (100 %), Rat (100 %), Xenopus laevis (100 %), Pig (100 %), Chicken (100 %), Bovine (100 %)

Characteristics: Rabbit polyclonal antibody to RACK1 (guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1)
RACK1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RACK1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot Assay-dependent dilution WB-Ag Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blotAssay-dependent dilution WB-AgAssay-dependent dilution

Comment:

Positive Control: Target recombinant protein

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GNB2L1

Target: GNB2L1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 2-Like 1 (GNB2L1))

Alternative Name: RACK1 (GNB2L1 Products)

Synonyms: MGC53289 antibody, GNB2L1 antibody, AL033335 antibody, GB-like antibody, Gnb2-rs1 antibody, Rack1 antibody, p205 antibody, RACK1 antibody, H12.3 antibody, HLC-7 antibody, PIG21 antibody, rack1 antibody, wu:fb80d08 antibody, wu:fk65d12 antibody, gnb2-rs1 antibody, h12.3 antibody, hlc-7 antibody, pig21 antibody, C12-3 antibody, c12.3 antibody, guanine nucleotide binding protein, beta 2, related sequence 1 antibody, receptor for activated C kinase 1 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 antibody, receptor for activated C kinase 1 L homeolog antibody, Guanine nucleotide-binding protein subunit beta-2-like 1 antibody, gnb2l1 antibody, RACK1 antibody, Rack1 antibody, rack1.L antibody, rack-1 antibody

Background: Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.

Cellular Localization: Cell membrane

Molecular Weight: 35 kDa

Gene ID: 10399

Pathways: cAMP Metabolic Process, Positive Regulation of Endopeptidase Activity