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ADRBK2 antibody (N-Term)

ADRBK2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855408
  • Target See all ADRBK2 Antibodies
    ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))
    Binding Specificity
    • 9
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 63
    • 31
    • 17
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 62
    • 1
    Rabbit
    Clonality
    • 61
    • 2
    Polyclonal
    Conjugate
    • 27
    • 7
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADRBK2 antibody is un-conjugated
    Application
    • 50
    • 40
    • 33
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Cow (Bovine)
    Cross-Reactivity (Details)
    Mouse (92 %), Rat (92 %), Zebrafish (84 %), Bovine (95 %)
    Characteristics
    Rabbit Polyclonal antibody to GRK3 (adrenergic, beta, receptor kinase 2)
    GRK3 antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human GRK3. The exact sequence is proprietary.
    Isotype
    IgG
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    Discover our top product ADRBK2 Primary Antibody
  • Application Notes
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Comment

    Positive Control: HeLa , Molt-4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.63 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ADRBK2 (Adrenergic, Beta, Receptor Kinase 2 (ADRBK2))
    Alternative Name
    GRK3 (ADRBK2 Products)
    Synonyms
    bark2 antibody, grk3 antibody, 4833444A01Rik antibody, AI851927 antibody, AW551196 antibody, Adrbk-2 antibody, Bark-2 antibody, GRK3 antibody, BARK2 antibody, Grk3 antibody, si:dz221d18.1 antibody, G protein-coupled receptor kinase 3 antibody, GRK3 antibody, grk3 antibody, Grk3 antibody
    Background
    The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85 % amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95 % similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

    Molecular Weight
    80 kDa
    Gene ID
    157
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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