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UAP1 antibody

UAP1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855661
  • Target See all UAP1 Antibodies
    UAP1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1 (UAP1))
    Reactivity
    • 36
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 4
    Rabbit
    Clonality
    • 32
    • 4
    Polyclonal
    Conjugate
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    This UAP1 antibody is un-conjugated
    Application
    • 32
    • 20
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to UAP1 (UDP-N-acteylglucosamine pyrophosphorylase 1)
    UAP1 antibody [N1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human UAP1. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: H1299

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Andres, Blong, Evans, Rumachik, Yamaguchi, Pham, Thompson, Kohler, Bertozzi: "Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation." in: ACS chemical biology, Vol. 12, Issue 8, pp. 2030-2039, (2018) (PubMed).

  • Target
    UAP1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1 (UAP1))
    Alternative Name
    UDP-N-acetylglucosamine pyrophosphorylase 1 (UAP1 Products)
    Synonyms
    fb63d12 antibody, fb64d12 antibody, zgc:55280 antibody, wu:fb63d12 antibody, wu:fb64d12 antibody, UAP1 antibody, agx antibody, agx1 antibody, agx2 antibody, spag2 antibody, AA420407 antibody, AA437972 antibody, AGX-1 antibody, AGX-2 antibody, AGX1 antibody, AgX antibody, ESTM38 antibody, SPAG2 antibody, AGX antibody, AGX2 antibody, RGD1561967 antibody, UDP-N-acetylglucosamine pyrophosphorylase 1 antibody, UDP-N-acetylglucosamine pyrophosphorylase 1 S homeolog antibody, UDP-N-acteylglucosamine pyrophosphorylase 1 antibody, UDP-N-acetylglucosamine pyrophosphorylase 1 L homeolog antibody, uap1 antibody, uap1.S antibody, UAP1 antibody, EUBREC_2612 antibody, uap1.L antibody, Uap1 antibody
    Background
    Converts UDP and GlcNAc-1-P into UDP-GlcNAc, and UDP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.

    Cellular Localization: Cytoplasm
    Molecular Weight
    59 kDa
    Gene ID
    6675
    UniProt
    Q16222
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