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BAK1 antibody (N-Term)

BAK1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2857046
  • Target See all BAK1 Antibodies
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    Binding Specificity
    • 18
    • 16
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 77
    • 32
    • 23
    • 16
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 71
    • 4
    • 2
    • 1
    Rabbit
    Clonality
    • 63
    • 15
    Polyclonal
    Conjugate
    • 44
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAK1 antibody is un-conjugated
    Application
    • 67
    • 27
    • 27
    • 19
    • 14
    • 13
    • 13
    • 13
    • 8
    • 7
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human
    Characteristics
    Rabbit Polyclonal antibody to BAK (BCL2-antagonist/killer 1)
    BAK antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human BAK. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product BAK1 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Validation: Orthogonal

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    BAK1 (BCL2-Antagonist/killer 1 (BAK1))
    Alternative Name
    BCL2 antagonist/killer 1 (BAK1 Products)
    Synonyms
    BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody
    Background
    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

    Cellular Localization: Membrane
    Molecular Weight
    23 kDa
    Gene ID
    578
    UniProt
    Q16611
    Pathways
    Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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