PDGF antibody
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- Target
- PDGF
- Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Cow (Bovine), Mouse (Murine), Pig (Porcine)
- Purification
- purified
- Immunogen
- PDGF antibody was raised in goat using purified human PDGF-AB as the immunogen.
- Isotype
- IgG
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- Application Notes
- Optimal conditions should be determined byt he investigator.
- Restrictions
- For Research Use only
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- Concentration
- Lot specific
- Buffer
- Affi-Gel Blue purified protein supplied in 0.1 M tris-glycine, pH 7.0.
- Handling Advice
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C.
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- Target
- PDGF
- Background
- Platelet derived growth factor receptor (PDGF Receptor) is a transmembrane glycoprotein of 170-185 kDa which undergoes homo or heterodimerization into complexes of alpha and beta subunits upon ligand binding, depending on the isoform of PDGF (PDGF AA, BB or AB) that binds. The phosphorylation of tyrosine residues in the now activated receptor can control multiple signaling events such as actin reorganization, transcription, cell growth, migration and differentiation.
- Molecular Weight
- 14-16 kDa (predicted detection band MW)
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