TNFRSF10A antibody (N-Term)
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- Target See all TNFRSF10A Antibodies
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNFRSF10A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- Recognizes the 57kD apoptosis related protein designated DR-4 (death receptor 4). DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL and thus DR-4 has also been called TRAIL-RI. DR4 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.
- Purification
- Ion exchange chromatography
- Immunogen
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Peptide from N-terminus of human DR4.
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product TNFRSF10A Primary Antibody
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- Application Notes
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Approved: WB (1:500 - 1:1000)
Usage: Western Blot: 1:500-1:1000. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))
- Alternative Name
- TNFRSF10A / DR4 (TNFRSF10A Products)
- Synonyms
- APO2 antibody, CD261 antibody, DR4 antibody, TRAILR-1 antibody, TRAILR1 antibody, TNFRSF10A antibody, TNF receptor superfamily member 10a antibody, tumor necrosis factor receptor superfamily member 26 antibody, tumor necrosis factor receptor superfamily, member 10a antibody, TNFRSF10A antibody, LOC510798 antibody
- Background
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Name/Gene ID: TNFRSF10A
Family: TNF Receptor
Synonyms: TNFRSF10A, APO2, CD261, DR4, TRAIL-R1, TRAILR-1, TRAILR1, TRAIL receptor 1, CD261 antigen, Cytotoxic TRAIL receptor, Death receptor 4 - Gene ID
- 8797
- Pathways
- Apoptosis, Positive Regulation of Endopeptidase Activity
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