Haptoglobin antibody

Catalog No. ABIN289212

Product Details anti-Haptoglobin Antibody

Target: Haptoglobin (HP)

Reactivity: Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This Haptoglobin antibody is un-conjugated

Application: Please inquire

Purification: Affinity chromatography purified

Immunogen: Haptoglobin antibody was raised in goat using highly purified bovine haptoglobin as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified fraction supplied in 10 mM Tris-HCl, 140 M NaCl, pH 7.4, with 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Haptoglobin

Target: Haptoglobin (HP)

Alternative Name: Haptoglobin (HP Products)

Synonyms: HP antibody, wu:fb64e01 antibody, BP antibody, HP2ALPHA2 antibody, HPA1S antibody, HP-1 antibody, HPR antibody, Zonulin antibody, haptoglobin antibody, haptoglobin-like antibody, HP antibody, hp antibody, Hp antibody, LOC479668 antibody, LOC101102413 antibody

Background: An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.

Pathways: Transition Metal Ion Homeostasis