CUBN antibody

Catalog No. ABIN289999

Product Details anti-CUBN Antibody

Target: CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUBN antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody was purified from rabbit serum by affinity chromatography.

Immunogen: Partial peptide of Rat Cubilin

Application Details

Application Notes: Working dilution Western Blotting: 2~5ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for CUBN

Target: CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))

Alternative Name: Cubilin (CUBN Products)

Synonyms: GP280 antibody, IFCR antibody, MGA1 antibody, AA408369 antibody, AL022750 antibody, D2Wsu88e antibody, gp280 antibody, cubilin antibody, cubilin (intrinsic factor-cobalamin receptor) antibody, LOC411053 antibody, CUBN antibody, cubn antibody, Cubn antibody

Background: Endocytic receptors Cubilin and Megalin are colocalized in the renal proximal tubule. Among the ligandsare vitamin transcobalamin(TC)-B12, vitamin D-binding protein(DBP), albumin, apolipoprotein (apoA-I) etc. From the fact renal failure is accompanied by the dysfunction of Cubilin, Cubilin is expected to involvethe disease development of kidney.This antibody was established from the purified serum of rabbits immunized with partial peptide of rat Cubilin. This antibody is useful for Western blotting.

Pathways: Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism