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CUBN antibody
CUBN
Reactivity: Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CUBN Antibody
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Target
See all CUBN Antibodies
CUBN
(Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
Reactivity
All reactivities for CUBN antibodies
Rat
Host
All hosts for CUBN antibodies
Rabbit
Clonality
All clonalities for CUBN antibodies
Polyclonal
Conjugate
All conjugates for CUBN antibodies
This CUBN antibody is un-conjugated
Application
All applications for CUBN antibodies
Western Blotting (WB)
Purification
This antibody was purified from rabbit serum by affinity chromatography.
Immunogen
Partial peptide of Rat Cubilin
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Alternatives
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Application Details
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Application Notes
Working dilution Western Blotting: 2~5ug/ml
Restrictions
For Research Use only
Handling
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Concentration
0.25 mg/ml
Buffer
PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)
Preservative
ProClin
Storage
-20 °C
Target Details for CUBN
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Target
CUBN
(Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
Alternative Name
Cubilin (CUBN Products )
Synonyms
GP280 antibody, IFCR antibody, MGA1 antibody, AA408369 antibody, AL022750 antibody, D2Wsu88e antibody, gp280 antibody, cubilin antibody, cubilin (intrinsic factor-cobalamin receptor) antibody, LOC411053 antibody, CUBN antibody, cubn antibody, Cubn antibody
Background
Endocytic receptors Cubilin and Megalin are colocalized in the renal proximal tubule. Among the ligandsare vitamin transcobalamin(TC)-B12, vitamin D-binding protein(DBP), albumin, apolipoprotein (apoA-I) etc. From the fact renal failure is accompanied by the dysfunction of Cubilin, Cubilin is expected to involvethe disease development of kidney.This antibody was established from the purified serum of rabbits immunized with partial peptide of rat Cubilin. This antibody is useful for Western blotting.
Pathways
Metabolism of Steroid Hormones and Vitamin D , Lipid Metabolism
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