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beta Amyloid 1-16 antibody

Reactivity: Human, Mouse WB, IF, IP, IHC, ELISA Host: Mouse Monoclonal Ab3 unconjugated
Catalog No. ABIN2961825
  • Target
    beta Amyloid 1-16
    Reactivity
    Human, Mouse
    Host
    • 2
    Mouse
    Clonality
    • 1
    • 1
    Monoclonal
    Conjugate
    • 2
    Un-conjugated
    Application
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA
    Specificity
    Reacts with humanand mouse Aβ1-16 as well as other Aβ peptides: Aβ37, Aβ38, Aβ39, Aβ40 and Aβ42
    Purification
    Purified
    Immunogen
    Synthetic peptide corresponding to Abeta1-16.
    Clone
    Ab3
    Isotype
    IgG1
  • Application Notes
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only:
    1 - 10 μg/mL for any applications
    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.4.
    Handling Advice
    Dilute in PBS or medium which is identical to that used in the assay system.
    Storage
    -20 °C
    Storage Comment
    Stable for at least one year at -20°C
    Expiry Date
    12 months
  • Target
    beta Amyloid 1-16
    Alternative Name
    Amyloid beta 1-16
    Background
    Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). There is now compelling evidence that metal binding to Aβ is involved in AD pathogenesis. The amino acid region 1-16 is widely considered as the metal binding domain of Aβ. Unlike copper(II) that prefers the N-terminal amino group as the main binding site, zinc(II) is preferentially placed in the 8-16 amino acidic region of Aβ (1-16).

    Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Gene name: APP, A4, AD1
    Gene ID
    351
    UniProt
    P05067
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