Decorin antibody

Catalog No. ABIN298189

Product Details anti-Decorin Antibody

Target: Decorin (DCN)

Reactivity: Human, Cow, Chicken

Host: Sheep

Clonality: Polyclonal

Conjugate: This Decorin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Recognizes human decorin. A small secreted chondroitin/dermatan sulfate proteoglycan, with a molecular weight of 90-140 kD. Decorin is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly.

Purification: Protein G purified

Immunogen: Synthetic peptide corresponding to the amino acids 6 - 19 of human decorin conjugated to Keyhole Limpet Haemocyanin.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P (2.5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 mg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: DCN / Decorin (DCN Products)

Synonyms: CSCD antibody, DSPG2 antibody, PG40 antibody, PGII antibody, PGS2 antibody, SLRR1B antibody, DC antibody, mDcn antibody, cscd antibody, dspg2 antibody, pg40 antibody, pgii antibody, pgs2 antibody, slrr1b antibody, decorin antibody, decorin L homeolog antibody, DCN antibody, Dcn antibody, dcn.L antibody, dcn antibody

Background: Name/Gene ID: DCN

Synonyms: DCN, CSCD, Decorin proteoglycan, PG-S2, PG40, Proteoglycan core protein, SLRR1B, Small leucine-rich protein 1B, PGII, PGS2, Bone proteoglycan II, Decorin, DSPG2

Gene ID: 1634

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process