Norrie Disease (Pseudoglioma) antibody (AA 25-133)
Quick Overview for Norrie Disease (Pseudoglioma) antibody (AA 25-133) (ABIN3015774)
Target
See all Norrie Disease (Pseudoglioma) (NDP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 25-133
-
Sequence
- KTDSSFIMDS DPRRCMRHHY VDSISHPLYK CSSKMVLLAR CEGHCSQASR SEPLVSFSTV LKQPFRSSCH CCRPQTSKLK ALRLRCSGGM RLTATYRYIL SCHCEECNS
-
Cross-Reactivity
- Mouse
-
Characteristics
- Polyclonal Antibodies
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-133 of human NDP (NP_000257.1).
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB,1:500 - 1:2000
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Norrie Disease (Pseudoglioma) (NDP)
-
Alternative Name
- NDP
-
Background
- This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy.,NDP,EVR2,FEVR,ND,norrin,Cell Biology & Developmental Biology,Growth factor,Neuroscience,Neurodegenerative Diseases,Stem Cells,NDP
-
Molecular Weight
- 15 kDa
-
Gene ID
- 4693
-
UniProt
- Q00604
-
Pathways
- Sensory Perception of Sound
Target
-