Norrie Disease (Pseudoglioma) antibody (AA 40-120)

Catalog No. ABIN7229934

The Rabbit Polyclonal anti-Norrie Disease (Pseudoglioma) antibody is suitable to detect Norrie Disease (Pseudoglioma) in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Norrie Disease (Pseudoglioma) antibody (AA 40-120) (ABIN7229934)

Target: Norrie Disease (Pseudoglioma) (NDP)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Norrie Disease (Pseudoglioma) antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Norrie Disease (Pseudoglioma) Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-NDP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NDP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NDP protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Norrie Disease (Pseudoglioma)

Target: Norrie Disease (Pseudoglioma) (NDP)

Alternative Name: NDP

Background: Norrie disease protein, X-linked exudative vitreoretinopathy 2 proteinNDP encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in NDP result in Norrie disease and X-linked exudative vitreoretinopathy.

Molecular Weight: 14kD

Gene ID: 4693

UniProt: Q00604

Pathways: Sensory Perception of Sound