Neuregulin 4 antibody (AA 1-115)

Catalog No. ABIN3016310

The Rabbit Polyclonal anti-Neuregulin 4 antibody (ABIN3016310) specifically detects Neuregulin 4 in IHC and WB. The antibody is reactive with Human samples.

Quick Overview for Neuregulin 4 antibody (AA 1-115) (ABIN3016310)

Target: Neuregulin 4 (NRG4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-Neuregulin 4 Antibody

Binding Specificity: AA 1-115

Sequence: MPTDHEEPCG PSHKSFCLNG GLCYVIPTIP SPFCRCVENY TGARCEEVFL PGSSIQTKSN LFEAFVALAV LVTLIIGAFY FLCRKGHFQR ASSVQYDINL VETSSTSAHH SHEQH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human NRG4 (NP_612640.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Neuregulin 4

Target: Neuregulin 4 (NRG4)

Alternative Name: NRG4

Background: The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR, MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008],NRG4,HRG4,Signal Transduction,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Neuroscience,NRG4

Molecular Weight: 12 kDa

Gene ID: 145957

UniProt: Q8WWG1

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway