Neuregulin 4 antibody
Quick Overview for Neuregulin 4 antibody (ABIN7240646)
Target
See all Neuregulin 4 (NRG4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human NRG4
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Isotype
- IgG
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Application Notes
- IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.3 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Neuregulin 4 (NRG4)
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Alternative Name
- NRG4
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Background
- Neuregulin 4also known asNRG4is a member of theneuregulinproteinfamily which in humans is encoded by theNRG4gene. Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.
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UniProt
- Q8WWG1
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Target
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