Neuregulin 4 antibody (AA 1-62)

Catalog No. ABIN7164313

Product Details anti-Neuregulin 4 Antibody

Target: Neuregulin 4 (NRG4)

Binding Specificity: AA 1-62

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuregulin 4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Pro-neuregulin-4, membrane-bound isoform protein (1-62AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Neuregulin 4

Target: Neuregulin 4 (NRG4)

Alternative Name: NRG4 (NRG4 Products)

Synonyms: HRG4 antibody, AI552600 antibody, neuregulin 4 antibody, NRG4 antibody, Nrg4 antibody, LOC100347220 antibody

Background:

Background: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors.

Aliases: DKFZp779N0541 antibody, DKFZp779N1944 antibody, Heregulin 4 antibody, HRG4 antibody, Neuregulin 4 antibody, Neuregulin-4 antibody, NRG-4 antibody, NRG4 antibody, NRG4_HUMAN antibody, pro-neuregulin-4, membrane-bound isoform antibody, Pro-NRG4 antibody

UniProt: Q8WWG1

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway