Integrin beta 2 antibody (ITGB2)

Details for Product anti-ITGB2 Antibody No. ABIN94003
Antigen
Reactivity
Cow (Bovine)
436
170
107
21
19
8
6
4
4
3
3
3
3
2
2
Host
Mouse
275
181
101
2
2
1
Clonality (Clone)
Monoclonal ()
Conjugate
This Integrin beta 2 antibody is un-conjugated
74
60
44
21
11
8
7
6
5
5
5
5
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)
338
238
143
126
88
58
56
52
39
39
10
9
9
7
6
1
1
1
1
1
Options
Immunogen Bovine leukocytes.
Clone IVA35
Isotype IgG1
Specificity The antibody IVA35 reacts with CD18 antigen (bovine), a 90-95 kDa type I transmembrane protein (integrin) expressed on all leukocytes.
Cross-Reactivity (Details) Bovine
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name CD18 (ITGB2 Antibody Abstract)
Pathways NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Product cited in: Dusinský, Tomásková, Horovská, Simon: "Monoclonal antibodies specific for bovine CD18." in: Folia biologica, Vol. 47, Issue 3, pp. 108-10, 2001 (PubMed).

Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, 1997 (PubMed).