TARBP2 antibody (C-Term)

Catalog No. ABIN3023980

Product Details anti-TARBP2 Antibody

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Primate

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TARBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein A Affinity Chromatography

Immunogen: A recombinant protein fragment within the C-terminal region of TARBP2 was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 5-10 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.

Target Details for TARBP2

Target: TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Alternative Name: TRBP2 (TARBP2 Products)

Synonyms: trbp antibody, trbp1 antibody, trbp2 antibody, MGC97783 antibody, TARBP2 antibody, LOQS antibody, TRBP antibody, TRBP1 antibody, TRBP2 antibody, fj51e12 antibody, wu:fj51e12 antibody, zgc:63778 antibody, Prbp antibody, TAR (HIV-1) RNA binding protein 2 antibody, TARBP2, RISC loading complex RNA binding subunit antibody, TAR (HIV-1) RNA binding protein 2 L homeolog antibody, TAR (HIV) RNA binding protein 2 antibody, tarbp2 antibody, TARBP2 antibody, tarbp2.L antibody, Tarbp2 antibody

Background: TARBP2 (TAR (HIV-1) RNA binding protein 2) , along with Dicer and Argonaute-2, is part of the RISC (RNA induced silencing complex). As part of the RISC, TRBP2 is important in viral defense. Dicer cleaves dsRNA into siRNA. Through TRBP2-Dicer interaction, the siRNA template is loaded onto Argonaute-2, which cleaves encountered viral mRNA strands complementary to the loaded siRNA base-pair sequence.

Gene ID: 6895

Pathways: Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization