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TSACC/C1orf182 antibody (Middle Region)

TSACC Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029276
  • Target See all TSACC/C1orf182 (TSACC) products
    TSACC/C1orf182 (TSACC) (TSSK6 Activating Co-Chaperone (TSACC))
    Binding Specificity
    • 15
    • 5
    Middle Region
    Reactivity
    Human, Mouse, Rat
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSACC/C1orf182 antibody is un-conjugated
    Application
    • 15
    • 13
    • 13
    • 7
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the middle region of human SIAH Interacting Protein (NTRWDYLTQVEKECKE) was used as the immunogen for this SIP antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the SIP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the SIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    TSACC/C1orf182 (TSACC) (TSSK6 Activating Co-Chaperone (TSACC))
    Alternative Name
    SIP (TSACC Products)
    Synonyms
    SIP antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, Teap antibody, p53DINP1 antibody, C1orf182 antibody, RP11-443G18.5 antibody, SSTK-IP antibody, 1700021C14Rik antibody, C3H1orf182 antibody, RGD1304953 antibody, tumor protein p53 inducible nuclear protein 1 antibody, TSSK6 activating cochaperone antibody, TSSK6 activating co-chaperone antibody, TP53INP1 antibody, TSACC antibody, Tsacc antibody
    Background
    CACYBP (Calcyclin-binding protein), also called SIP (SIAH Interacting Protein), is a protein that in humans is encoded by the CACYBP gene. The full-length SIP cDNA encodes a predicted 228-amino acid protein. Sequence analysis of the shortest cDNA derived by 2-hybrid screening revealed an 8-amino acid difference in the deduced open reading frame followed by a stop codon, resulting in a predicted 80-amino acid protein, SIP-short (SIPS). The CACYBP gene is mapped on 1q25.1. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. The C-terminal region of SIP that is homologous to SGT1 was able to complement defects in yeast strains containing SGT1 mutant alleles, demonstrating conservation of SGT1 and SIP protein function.
    UniProt
    Q9HB71
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