ZEB2 antibody (AA 1-200)

Catalog No. ABIN3029672

Product Details anti-ZEB2 Antibody

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZEB2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-200) was used as the immunogen for this ZEB2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ZEB2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ZEB2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ZEB2

Target: ZEB2 (Zinc Finger E-Box Binding Homeobox 2 (ZEB2))

Alternative Name: ZEB2 (SIP1) (ZEB2 Products)

Synonyms: ZFHX1B antibody, Zfhx1b antibody, HSPC082 antibody, SIP-1 antibody, SIP1 antibody, SMADIP1 antibody, 9130203F04Rik antibody, D130016B08Rik antibody, Zfx1b antibody, Zfxh1b antibody, mKIAA0569 antibody, XSip1 antibody, sip1 antibody, zfhx1b antibody, si:dkey-52o2.2 antibody, sip1a antibody, wu:fc92g08 antibody, sip1b antibody, zinc finger E-box binding homeobox 2 antibody, zinc finger E-box binding homeobox 2 S homeolog antibody, zinc finger homeobox protein antibody, zinc finger E-box binding homeobox 2a antibody, zinc finger E-box binding homeobox 2b antibody, ZEB2 antibody, Zeb2 antibody, zeb2.S antibody, zeb2 antibody, zeb2a antibody, zeb2b antibody

Background: Zinc finger E-box-binding homeobox 2, also known as SIP1 or Zinc finger homeobox 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The gene is a member of the ZEB1/Drosophila Zfh1 family of two-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated< a href=../search_result.php?search_txt=smad>SMADs, the transducers of< a href=../search_result.php?search_txt=tgf beta>TGF-betasignaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated following< a href=../search_result.php?search_txt=snai1>SNAI1expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.

Gene ID: 9839

Pathways: Tube Formation