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CXCR2 antibody

CXCR2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030509
  • Target See all CXCR2 Antibodies
    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
    Reactivity
    • 77
    • 38
    • 23
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 70
    • 10
    • 1
    • 1
    Rabbit
    Clonality
    • 72
    • 9
    • 1
    Polyclonal
    Conjugate
    • 45
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR2 antibody is un-conjugated
    Application
    • 50
    • 31
    • 21
    • 18
    • 16
    • 13
    • 13
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    Amino acids CYEDMGNNTANWRMLLR were used as the immunogen for this CXCR2 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product CXCR2 Primary Antibody
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the CXCR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the CXCR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
    Alternative Name
    CXCR2 (CXCR2 Products)
    Synonyms
    CD182 antibody, CDw128b antibody, CMKAR2 antibody, IL8R2 antibody, IL8RA antibody, IL8RB antibody, CXC-R2 antibody, CXCR-2 antibody, CD128 antibody, CDw128 antibody, Cmkar2 antibody, Gpcr16 antibody, IL-8Rh antibody, IL-8rb antibody, Il8rb antibody, mIL-8RH antibody, C-X-C motif chemokine receptor 2 antibody, chemokine (C-X-C motif) receptor 2 antibody, Cxcr2 antibody, CXCR2 antibody
    Background
    CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family(subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
    UniProt
    P25025
    Pathways
    cAMP Metabolic Process
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